The Corr Research Group at Rensselaer Polytechnic Institute is dedicated to investigating the mechanical and biochemical factors that drive musculoskeletal pathologies and solid tumor progression. We are currently investigating an embryonic-inspired approach for generation of tendon and muscle fibers with improved lifetimes and mechanical properties over current tissue-engineered replacements. We have also pioneered a laser-direct write bioprinting method for the fabrication of spatially-precise 3D cellular microenvironments, which we are using to develop mechanically biomimetic in vitro tumor models.
FEATURED
The Corr lab at RPI and their collaborators at Albany Medical Center were featured by the American Society of Mechanical Engineering for their work in developing 3D bioprinting and imaging techniques designed to generate and analyze tumor models outside the body.... “To achieve that, we have to not only develop new 3D bioprinting techniques to generate tumor models with prescribed cell composition and architecture, but also new imaging techniques to visualize how different drugs interact with cancer cells depending on where they are located within these tumor models.”
Researchers at Rensselaer Polytechnic Institute and Albany Medical Center are working together to develop three-dimensional bioprinting and imaging techniques that will generate and analyze tumor models in the laboratory, with the goal of accelerating the development and optimization of personalized anti-cancer drugs.
Michael Bramson, a 1st year PhD student in the Corr lab, was on one of three winning teams at the 2nd annual Mount Sinai Health Hackathon, and his team was awarded $2500 for their innovative platform Streamline, a web-based service designed to use natural language processing in assisting researchers write clinical trial applications and protocols
Preliminary results of stem cell research projects sponsored by the Center for Biotechnology and Interdisciplinary Studies (CBIS) were displayed during a poster session and researcher networking lunch held December 2, in the CBIS auditorium and the Senator William H. Hernstadt ’57 and Jerene Yap Hernstadt Gallery.
Using a novel direct-writing method at RPI, Dr. Corr is fabricating combinatorial libraries of scaffold, biomolecule, and stem cell constructs with single-cell spatial resolution.
David T. Corr, assistant professor in the Department of Biomedical Engineering at Rensselaer Polytechnic Institute, has won a Faculty Early Career Development Award (CAREER) from the National Science Foundation (NSF).